Pharmacokinetic and bioequivalence comparison of a single 100-mg dose of cefteram pivoxil powder suspension and tablet formulations: a randomized-sequence, open-label, two-period crossover study in he
- 作者：Jianjun Zou ; Bin Di ; Chun Yong Wu ; Qin Hu ; Jian Hua Li ; Yubing Zhu ; Hongwei Fan ; DaWei Xiao ; Guang Ji Wang
- 关键词：bioavailability ; bioequivalence ; cefteram ; pivoxil ; human plasma ; high-performance liquid ; chromatography ; Chinese ; pharmacokinetics
- 刊名：Clinical Therapeutics
- 出版年：2008
- 期刊代码：65_01492918
- 类别：med
- 出版时间：April 2008
- 卷：30
- 期：4
- 页码：654-660
- 文件大小：878 K
摘要
Background: Cefteram pivoxil (CFTM-PI) is an oral antibiotic available in powder suspension and tablet formulations indicated in China for the treatment of bacterial infections. Although these 2 formulations are marketed in China, published information regarding their pharmacokinetics and bioequivalence in the Chinese population is not available.