Radiochemotherapy in Patients With Primary Glioblastoma Comparing Two Temozolomide Dose Regimens
- 作者：Stephanie E. Combs ; Johanna Wagner ; Marc Bischof ; Thomas Welzel ; Lutz Edler ; Renate Rausch ; Florian Wagner ; Angelika Zabel-du Bois ; Jü ; rgen Debus ; Daniela Schulz-Ertner
- 关键词：Glioblastoma ; Radiochemotherapy ; Temozolomide ; Outcome ; Toxicity
- 刊名：International Journal of Radiation Oncology*Biology*Physics
- 出版年：2008
- 期刊代码：136_03603016
- 类别：med
- 出版时间：15 July 2008
- 卷：71
- 期：4
- 页码：999-1005
- 文件大小：799 K
摘要
The combination of Ni(0) and an N-heterocyclic carbene acts as a precatalyst for the cycloisomerization of enynes to afford 1,3-dienes. During the course of the reaction, a nickel hydride is formed from oxidative addition of the ortho C–H on the carbene ligand. Deuterium labeling studies are presented.