Production and resolution of cantharidin-induced inflammatory blisters
- 作者：Maglio ; Dana ; Nightingale ; Charles H. ; Nicolau ; David P.
- 关键词：Cantharidin ; Blisters ; Healing
- 刊名：International Journal of Antimicrobial Agents
- 出版年：2003
- 期刊代码：126_09248579
- 类别：med
- 出版时间：July, 2003
- 卷：22
- 期：1
- 页码：77-80
- 文件大小：235 K
摘要
While inflammatory blisters have long been utilized as a means of evaluating antimicrobial disposition to aid in the development of new treatments for skin and skin structure infections, sparse data are available regarding the healing of the blisters once the experiment has been completed. We report the blister induction technique and resolution time in ten volunteers enrolled in a pharmacokinetic study using the cantharidin-induced inflammatory blister technique.