S100B is expressed in, and released from, OLN-93 oligodendrocytes: Influence of serum and glucose deprivation
- 作者：J. Steiner ; H.-G. Bernstein ; B. Bogerts ; T. Gos ; C. Richter-L ; sberg ; M.T. Wunderlich ; G. Keilhoff
- 关键词：astrocytes ; oligodendrocytes ; OLN-93 ; RAGE ; S-100B ; S100 beta
- 刊名：Neuroscience
- 出版年：2008
- 期刊代码：50_03064522
- 类别：neu
- 出版时间：23 June 2008
- 卷：154
- 期：2
- 页码：496-503
- 文件大小：2407 K
摘要
S100B (member of a family of proteins that are 100%soluble in ammonium sulfate at neutral pH) has been widely used as astrocyte marker in animal models and in human brain diseases. Recent studies revealed S100B-immunopositivity in oligodendrocytes and O2A oligodendroglial progenitor cells. It is unknown, however, if oligodendrocytes produce S100B themselves, or if the S100B-immunolabeling is caused by binding or absorption of the protein.