Photothermal microfluidic sensor based on an integrated Young interferometer made by ion exchange in glass

详细信息	查看全文 | 推荐本文 |

• 作者：A. Schimpf^a ; ^{armin.schimpf@minatec.inpg.fr}  ; [Author Vitae] ; D. Bucci^a  ; [Author Vitae] ; M. Nannini^c  ; [Author Vitae] ; A. Magnaldo^b  ; [Author Vitae] ; L. Couston^b  ; [Author Vitae] ; J.-E. Broquin^a  ; [Author Vitae]
• 关键词：Borosilicate ; Chemical analysis ; Chemical sensor ; Ion exchange ; Lab-on-a-chip ; Microfluidics ; Online monitoring ; Optofluidics ; Photothermal ; PTPS ; Thermal-lens spectrometry ; Young interferometer
• 刊名：Sensors and Actuators B ; Chemical
• 出版年：2012
• 期刊代码：161_09254005
• 类别：et
• 出版时间：1 March, 2012
• 卷：163
• 期：1
• 页码：29-37
• 文件大小：845 K

摘要

We present the planar co-integration of an ion-exchange Young interferometer with a microfluidic sensing chamber for photothermal analyte detection. Being exclusively fabricated and packaged in borosilicate glass, the sensor is well suited for a vast range of applications in chemical analysis, including ionizing environments. Local absorption of a pulsed excitation laser by the analyte in the fluid generates a change of the fluid refractive index which translates to a shift of the interference pattern. The detection limit of fringe movement was measured to be 1.8 脳 10^鈭? 脳 2蟺 and the corresponding refractive index resolution was 螖n = 7.5 脳 10^鈭?. Absorption measurements of cobalt(II) nitrate in ethanol yielded a detection limit of c = 6 脳 10^鈭? M, equivalent to an absorption coefficient of 伪 = 1.2 脳 10^鈭? cm^鈭? and a minimum detectable absorbance of K = 1.4 脳 10^鈭?. At a probed volume of 20 pl, a quantity of 12 fmol of Co(II) was detected.