Electrochemical synthesis and characterization of Fe₇₀Pd₃₀ nanotubes for drug-delivery applications

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• 作者：K. Ž ; už ; ek Rož ; man^a ; ^{tina.zuzek@ijs.si} ; D. Peč ; ko^a ; S. Š ; turm^a ; U. Maver^b ; P. Nadrah^b ; M. Bele^b ; S. Kobe^a
• 关键词：Intermetallic compounds ; Nanostructures ; Magnetic properties ; Drug delivery
• 刊名：Materials Chemistry and Physics
• 出版年：2012
• 期刊代码：58_02540584
• 类别：ms
• 出版时间：15 March, 2012
• 卷：133
• 期：1
• 页码：218-224
• 文件大小：986 K

摘要

Fe-Pd-based tubular nanostructures were prepared by direct electrodeposition into track-etched polycarbonate templates. The characterization of the electrodeposition process showed that the complexing of Pd and Fe is necessary for the co-deposition of both metals. In the as-deposited nanotubes, which exhibited an overall composition of Fe₇₀Pd₃₀ as determined by SEM/EDS, a gradient in the composition along the tubes was observed using a detailed TEM/EDS analysis. This was attributed to potentiostatic nature of the deposition and to different kinetic properties at the beginning of the reaction, and later on, when the reaction is diffusion controlled, to different transport properties (diffusion and convection) of the involved ionic species. The magnetic measurements showed that the Fe₇₀Pd₃₀ nanotubes are ferromagnetic with a high magnetization saturation of 170 emu g^鈭?, which makes them suitable for drug-delivery applications. The Fe₇₀Pd₃₀ nanotubes were successfully functionalized with a model drug, paracetamol. The proposed type of release, with an initial burst and a slower release of the remaining drug, could be suitable for applications where a fast action is required, which then has to be maintained for a certain time period.