Dexmedetomidine as sole sedative for awake intubation in management of the critical airway

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• 作者：Basem Abdelmalak ; Laila Makary ; Jeremy Hoban ; D. John Doyle
• 关键词：Dexmedetomidine ; Difficult airway ; Awake intubation ; Fiberoptic bronchoscopy ; Sedation
• 刊名：Journal of Clinical Anesthesia
• 出版年：2007
• 期刊代码：147_09528180
• 类别：med
• 出版时间：August 2007
• 卷：19
• 期：5
• 页码：370-373
• 文件大小：94 K

摘要

We report a series of successful awake fiberoptic intubations in patients with critical (unstable, difficult) airways using the α₂-agonist, dexmedetomidine. Dexmedetomidine has several desirable pharmacologic properties, including sedation, anxiolysis, hypnosis, analgesia, amnesia, antisialagogue effects, and a unique respiratory-sparing effect. Dexmedetomidine appears to be a useful agent for sedation during awake fiberoptic intubation in difficult airway patients.