• 作者：J. Mucientes Rasilla^a ; ^{jorgemuci@vodafone.es} ; J. Cardona Arbonié ; s^a ; R. Delgado Bolton^a ; L. Izarduy Pereyra^a ; G. Salazar Andí ; a^a ; A. Prieto Soriano^a ; R. Anula Ferná ; ndez^b ; J. Mayol Martí ; nez^b ; L. Lapeñ ; a Gutié ; rrez^a ; A. Gonzá ; lez Maté ; ^a ; J. Luis Carreras Delgado^a
• 关键词：SPECT-TAC ; Linfogammagrafí ; a ; Ganglio centinela ; Melanoma ; Fusió ; n
• 刊名：Revista Espa帽ola de Medicina Nuclear
• 出版年：2009
• 期刊代码：pca315_02126982
• 类别：med
• 出版时间：September-October 2009
• 卷：28
• 期：5
• 页码：229-234
• 文件大小：223 K

Introduction

The prognosis of patients with cutaneous melanoma is greatly influenced by the presence of lymph node metastases. One of the most innovative and fascinating concepts to emerge in the field of oncology in recent years is the use of sentinel lymph node biopsy (SLNB).

Aim

The aim of this study was to determine what SPECT-CT images contribute to the search for sentinel nodes in patients with melanoma.

Methods

From March 2007 to October 2008, 18 patients were examined for sentinel nodes using dynamic scintigraphy, planar images, and SPECT-CT in the Nuclear Medicine Department of San Carlos University Hospital. The group contained 10 women and 8 men, age range 14鈥?3 years, mean age 57 years (57卤20.1).

Results

The sentinel node was located by conventional imaging techniques (dynamic scintigraphy and planar images) in 16 of 18 patients (88.88%). SPECT-CT identified the sentinel node in 18 of 18 patients (100%) and detected clinically relevant findings in 6 of 18 patients (33.33%)

Conclusions

SPECT-CT imaging contributed clinically relevant information on sentinel nodes of melanoma, which is particularly important in patients with melanoma of the trunk or head and neck.