• 作者：L. Rodrí ; guez-Bel^a ; ^{musgui63@hotmail.com} ; J. Mora Salvad&#243 ; ^a ; M. Bajé ; n Lá ; zaro^a ; R. Puchal Añ ; é ; ^a ; I. Sancho Kolster^a ; S. Guirao Marí ; n^a ; A. Domé ; nech Vilardell^a ; C. Sá ; nchez Catasus^c ; M. Font Padr&#243 ; s^b ; Y. Krupinspy^b ; J. Martí ; n Comí ; n^a
• 关键词：Enfermedad cerebrovascular ; Tomografí ; a computarizada de emisió ; n de fotó ; n ú ; nico de perfusió ; n cerebral ; Mapas estadí ; sticos paramé ; tricos
• 刊名：Revista Espa帽ola de Medicina Nuclear
• 出版年：2010
• 期刊代码：pca315_02126982
• 类别：med
• 出版时间：January-February 2010
• 卷：29
• 期：1
• 页码：3-7
• 文件大小：168 K

The efficacy of carotid endartectomy (CE) in cerebrovascular accidents produced by carotid stenosis can be evaluated with the cerebral perfusion with single photon emission tomography, using statistical parametric mapping (SPM).

Material and methods

Twelve patients with significant carotid stenosis who underwent endartectomy were included in the study. All underwent a cerebral perfusion study with 99mTc-etilen cisteinato dietilester (ECD) at baseline and after the endartectomy. Using SPM, the baseline/post-surgery study was compared independently with the control group made up of 20 patients and the corresponding parametric statistical mappings were obtained. Changes in extension (k_E or voxel number) and intensity (change in the T value) of the significantly hypoperfused zones and direction of these changes were evaluated.

Results

In the group of 12 patients, improvement of the post-surgical cerebral perfusion was observed in 5 patients with an average 50.56%decrease in the extension of the hypoperfused zones and average 30.9%decrease of intensity. Four patients showed an average 85.53%increase in the extension of cerebral hypoperfusion and of 34.21%in intensity. No significant changes between both studies were found in three patients.

Conclusions

SPM has been shown to be a useful tool that makes it possible to objectify the cerebral brain flow changes produced after the surgical intervention, evaluating the changes in extension and intensity of the significantly hypoperfused zones.