• 作者：M.J. Torres Valdivieso ; ^{mjtorresv@wanadoo.es} ; J. Rodrí ; guez Ló ; pez ; E. Gó ; mez Castillo ; G. Bustos Lozano ; E. Bergó ; n Sendin ; C.R. Pallá ; s Alonso
• 关键词：Recié ; n nacido de muy bajo peso ; Seguimiento ; Discapacidad ; Secuelas ; Pará ; lisis cerebral ; Supervivencia
• 刊名：Anales de Pediatr铆a
• 出版年：2010
• 期刊代码：pca47_16954033
• 类别：med
• 出版时间：June 2010
• 卷：72
• 期：6
• 页码：377-384
• 文件大小：555 K

Introduction

Advances in perinatal care have resulted in increased survival rates for extremely low birth weight children, but it is fundamental to know if these improved survival rates have been accompanied by increased impairment rates.

Objective

To compare, over two different time periods, the survival and disability rates at 2 years of corrected age, among newborns 鈮?2 weeks and weighed 鈮?500 g at birth.

Methodology

Follow-up study that included 963 children born in the hospital between 1991 and 2004 who met the study criteria. Neonatal morbidity, mortality and disability to 2 years of corrected age in 2 time periods 1991鈥?998 (period I) and 1999鈥?004 (period II) have been evaluated and analysed by subgroups of weight (weight <1000 g and 1000鈥?500 g).

Results

Mortality decreased significantly during the second period, both for children with birth weight <1000 g (32%vs 44%) as for those with birth weight between 1000 and 1500 g ( 3,6%vs 9%). Analysing all children 鈮?500 g, an increase in the survivors without disability was observed in the second period (69%vs 60%, p=0.003); but by subgroups this increase only was significant in children with birth weight 1000鈥?500 g (67%vs 82%).

Conclusions

In our study, globally analysing all children with birth weight 鈮?500 g, it can be seen that there has been an increase in survival without an increase in the frequency of disabilities. Analysing by weight subgroups, survival has increased in both groups, but disability has decreased only in the birth weight 1000鈥?500 g subgroup.