Infants younger than 1 year who had a CVC placed at our center from 2005 to 2009 were reviewed. Patients with ultrasonically diagnosed DVT were compared to those without radiographic evidence.
Of 333 patients, 47%(155/333) had femoral, 33%(111/333) had jugular, and 19%(64/333) had subclavian CVCs. Deep venous thromboses occurred in 18%(60/333) of patients. Sixty percent (36/60) of DVTs were in femoral veins. Femoral CVCs were associated with greater DVT rates (27%; 42/155) than jugular (11%; 12/111) or subclavian CVCs (9%; 6/64; P < .01). There was a 16%DVT rate in those with saphenofemoral Broviac CVCs vs 83%(20/24) in those with percutaneous femoral lines (P < .01). Multilumen CVCs had higher DVT rates than did single-lumen CVCs (54%vs 6%, P < .01), and mean catheter days before DVT diagnosis was shorter for percutaneous lines than Broviacs (13 卤 17 days vs 30 卤 37 days, P = .02). Patients with +DVT had longer length of stay (86 卤 88 days vs 48 卤 48 days, P < .01) and higher percentage of intensive care unit admission (82%vs 70%, P = .02).
Deep venous thrombosis reduction strategies in infants with CVCs include avoiding percutaneous femoral and multilumen CVCs, screening percutaneous lines, and early catheter removal.