• 作者：Mariana Cerda-Esteve^a ; ^{mariaina.cerda@gmail.com} ; Agustí ; n Ruiz-Gonzá ; lez^b ; Mindaugas Gudelis^c ; Albert Goday^d ; Javier Trujillano^e ; Elisa Cuadrado^f ; Juan Francisco Cano^d
• 关键词：Hiponatremia ; Neurologí ; a ; Incidencia
• 刊名：Endocrinolog铆a y Nutrici贸n
• 出版年：2010
• 期刊代码：pca151_15750922
• 类别：med
• 出版时间：May 2010
• 卷：57
• 期：5
• 页码：182-186
• 文件大小：154 K

Introduction

Hyponatremia is considered the most frequent electrolyte disorder found in hospitalized patients and seems to be a prognostic factor during hospitalization.

Methods

A prospective observational study was carried out in consecutive neurological patients admitted to our hospital over a 3-month period. Blood and urinary ionogram and osmolality were determined at entry and 3鈥? days after admission in all patients with hyponatremia.

Results

Of the 130 patients admitted, 19 (14.6%) had hyponatremia. The causes of hyponatremia were as follows: inappropriate fluid replacement in 4 patients (21%), antihypertensive drugs in 4 (21%), syndrome of inappropriate secretion of antidiuretic hormone in 4 (21%), cerebral salt wasting syndrome in 2 (10%), and edematous status caused by liver disease in one and digestive loss in one (5%) each. Mortality was one (5%) and 0 (0%) among patients with and without hyponatremia, respectively.

Conclusion

Hyponatremia is common in hospitalized neurological patients and can be misdiagnosed as a worsening of the main illness.