The aim of this work is to study different compositions in the Ga–Ge–Sb–S system for the definition of two compositions compatible with the elaboration of a single-mode fiber at the 1.55 μm telecom wavelength. The variations of the glass transition temperature (
Tg), the dilatation coefficient (
) and the refractive index (
n) have been studied for two glasses series: Ga
xGe
25−xSb
10S
65 (series 1), Ga
5Ge
25−xSb
10S
60+x (series 2). This study has
lead to the choice of the Ga
4Ge
21Sb
10S
65 composition as clad glass for the preparation of the single-mode fiber and Ga
5Ge
20Sb
10S
65 composition as the core. The discrepancies for the studied parameters between the core and clad compositions are the following: Δ
< 2%, Δ
Tg < 3%and Δ
n = 5 × 10
−3. Finally a single-mode fiber has been prepared by the rod in tube technique.