- 作者：Po-Jen Ko ; M.D.&lowast ; ; Yen Chu ; Ph.D.&lowast ; ; Yi-Cheng Wu ; M.D.&lowast ; ; Chieng-Ying Liu ; M.D.&lowast ; ; Ming-Ju Hsieh ; M.D.&lowast ; ; Tzu-Ping Chen ; M.D.&lowast ; ; Yin-Kai Chao ; M.D.&lowast ; ; Ching-Yang Wu ; M.D.&lowast ; ; Hsu-Chia Yuan ; B.S.&lowast ; ; Yun-Hen Liu ; M.D.&lowast ; ; foreverairmail@gmail.com ; Hui-Ping Liu ; M.D.&dagger ;
- 关键词：natural orifice surgery ; natural orifice transluminal endoscopic surgery ; NOTES ; transoral approach
- 刊名：Journal of Surgical Research
- 出版年：2012
- 期刊代码：299_00224804
- 类别：med
- 出版时间：15 June, 2012
- 卷：175
- 期：2
- 页码：207-214
- 文件大小：848 K
Background
The thoracic cavity approach for natural orifice transluminal endoscopic surgery (NOTES) is technically challenging. The aim of this study was to evaluate the feasibility of a transoral endoscopic technique for a surgical lung biopsy and pericardial window creationMethods
Under general anesthesia, a 12 mm incision was made over the vestibulum oris region. Under video guidance, a homemade metallic tube was introduced through the incision, extending along the pre-tracheal space to the substernal space with blunt dissection technique, and used as the entrance into the thoracic cavity. A surgical lung biopsy and a pericardial window creation were performed in 12 canines, using the transoral NOTES technique.
Results
The transoral endoscopic surgical lung biopsy and pericardial window creation were successfully completed in 11 of the 12 canines. Intraoperative bleeding and death from an injury to the pulmonary hilum developed in one animal during the electrosurgical excision of lung tissue.
Conclusions
Transoral surgical lung biopsy and pericardial window creation in canine models is technically feasible and can be used as a novel experimental platform for studies of NOTES for intra-thoracic surgery.