Swallowing difficulty in Parkinson's disease
- 作者：Fuh ; Jong-Ling ; Lee ; Rheun-Chuan ; Wang ; Shuu-Jiun ; Lin ; Cheng-Huai ; Wang ; Pei-Ning ; Chiang ; Jen-Huey ; et. al.
- 关键词：Dysphagia ; Parkinson's disease ; Swallowing ; Videofluoroscopy
- 刊名：Clinical Neurology and Neurosurgery
- 出版年：1997
- 期刊代码：60_03038467
- 类别：med
- 出版时间：May, 1997
- 卷：99
- 期：2
- 页码：106-112
- 文件大小：578 K
摘要
Dysphagia is a frequent and potentially serious complication of Parkinson's disease (PD). We examined the oropharyngeal swallowing ability in 19 PD patients (15 men and 4 women, mean age 68.42 years, mean Hoehn and Yahr stage 1.8) using modified barium swallow before and after administering oral levodopa (in combination with benserazide). Twelve (63.2%) patients demonstrated objective evidence of swallowing abnormalities; although only six patients (31.6%) had subjective complaints. Vallecula sinus and pyriform sinus residues were the most frequent abnormalities (47.4%and 42.1%); followed by delayed swallowing reflex (26.3%). Three patients demonstrated silent aspiration. In the 12 patients with abnormal swallowing, six (50%) showed objective improvement after levodopa treatment, while the remaining six showed no change. Of the former group of six, one patient showed improvement in the oral phase, but deterioration in the pharyngeal phase. We concluded that PD patients had a high percentage of objective swallowing abnormalities which could be reduced in half of the patients through the administration of levodopa treatment.