Omic techniques in systems biology approaches to traditional Chinese medicine research: Present and future

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• 作者：Alessandro Buriani^a ; ^b ; ^c ; ¹ ; Maria L. Garcia-Bermejo^d ; ^e ; ¹ ; Enrica Bosisio^f ; Qihe Xu^g ; Huige Li^h ; Xuebin Dongⁱ ; Monique S.J. Simmonds^j ; Maria Carrara^b ; Noelia Tejedor^e ; Javier Lucio-Cazana^e ; Peter J. Hylands^a ; ^{peter.2.hylands@kcl.ac.uk}
• 关键词：Genomics ; Transcriptomics ; Metabolomics ; Metabonomics ; Proteomics ; Traditional Chinese medicine ; Chinese herbal medicine
• 刊名：Journal of Ethnopharmacology
• 出版年：2012
• 期刊代码：26_03788741
• 类别：pha
• 出版时间：10 April, 2012
• 卷：140
• 期：3
• 页码：535-544
• 文件大小：529 K

摘要

Omic techniques have become key tools in the development of systems biology. As the holistic approaches underlying the practice of traditional Chinese medicine (TCM) and new tendencies in Western medicine towards personalised medicine require in-depth knowledge of mechanisms of action and active compounds, the use of omic techniques is crucial for understanding and interpretation of TCM development, especially in view of its expansion in Western countries. In this short review, omic applications in TCM research are reviewed which has allowed some speculation regarding future perspectives for these approaches in TCM modernisation and standardisation. Guidelines for good practice for the application of omics in TCM research are also proposed.