ORAC of chitosan and its derivatives

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• 作者：Luca Casettari^a ; ^{luca.casettari@uniurb.it} ; Lorenzo Gennari^b ; ^{lorenzo.gennari@uniurb.it} ; Donato Angelino^b ; ^{donato.angelino@uniurb.it} ; Paolino Ninfali^b ; ^{paolino.ninfali@uniurb.it} ; Enzo Castagnino^a ; ^{enzo.castagnino@uniurb.it}
• 关键词：Chitosan ; ORAC ; Antiradical activity ; N-acetyl cysteine-g-chitosan ; Gallic acid-g-chitosan
• 刊名：Food Hydrocolloids
• 出版年：2012
• 期刊代码：37_0268005x
• 类别：ch
• 出版时间：August, 2012
• 卷：28
• 期：2
• 页码：243-247
• 文件大小：312 K

摘要

Chitosan and chitosan derivatives are receiving a lot of attention as materials of natural origin which possess radical scavengers, antioxidants and antimicrobial properties, especially in food applications. With the aim to apply the Oxygen-Radical Absorbance Capacity assay (ORAC), to detect the polysaccharides capacity to scavenge the peroxyl radical, four different grafted chitosan derivatives were synthesized.

Among the synthesized derivatives, N-acetyl cysteine-g-chitosan was found to have the highest ORAC value, while gallic acid-g-chitosan and p-hydroxybenzoic acid-g-chitosan had respective 70%and 42%of ORAC values of the former. On the contrary, p-methoxybenzoic acid-g-chitosan did not show any significant difference in antioxidant activity from the unmodified chitosan. A linear correlation between ORAC values and total phenols measured with the Folin-Ciocalteau reagent was shown. The combination of ORAC and Folin-Ciocalteau assays is a useful system to monitor the growth of the acquired antioxidant capacity in relation to the type of phenolic compound used for grafting.