Asymmetric Michael reaction: novel efficient access to chiral β-ketophosphonates

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• 作者：S ; rine Delarue-Cochin ; Jian-Jung Pan ; Auré ; lie Dauteloup ; Fré ; dé ; ric Hendra ; Roger Gagali Angoh ; Delphine Joseph ; Philip J. Stephens ; Christian Cavé
• 刊名：Tetrahedron ; Asymmetry
• 出版年：2007
• 期刊代码：108_09574166
• 类别：ch
• 出版时间：30 March 2007
• 卷：18
• 期：5
• 页码：685-691
• 文件大小：243 K

摘要

The asymmetric Michael reaction between chiral β-enaminophosphonates derived from (S)-1-phenylethylamine and various electrophilic alkenes furnished β,β-disubstituted ketophosphonates in good yields and with excellent enantioselectivity.