À propos d'un cas d'allo-immunisation anti-JK1 non dépisté sur plasma
- 作者：B. Clavier ; R. Hadef ; C. Ait Mansour ; G. Janus ; M. Joussemet
- 关键词：Anti-JK1 antibody ; Detection of irregular antibodies ; Plasma
- 刊名：Transfusion Clinique et Biologique
- 出版年：2006
- 期刊代码：249_12467820
- 类别：med
- 出版时间：October 2006
- 卷：13
- 期：4
- 页码：266-268
- 文件大小：114 K
摘要
The sensitivity of the detection of irregular antibodies (DIA) is one of the fundamental bases of transfusion safety. Its implementation is specified in accordance with a very specific framework that allows the use of serum or plasma. The case reported here points out a failure to detect irregular antibodies in plasma sample. Thus a low intensity anti-JK1 antibody detected and identified in serum slipped through unnoticed in plasma. The difficulties to detect and identify this antibody, well-known as a deceptive and dangerous one, are being discussed in order to better assess the limitations of DIA.