• 作者：Josep M. Alegret^a ; ^{txalegret@hotmail.com} ; Xavier Viñ ; olas^b ; Juliá ; n Villacastí ; n^c ; Juan G. Martí ; nez^d ; Nicolá ; s Pachó ; n^e ; Francisco Crespo^f ; en nombre de los investigadores del registro REVERSE
• 关键词：Fibrilaci&oacute ; n auricular ; Cardioversi&oacute ; n ; Anticoagulaci&oacute ; n
• 刊名：Medicina Cl铆nica
• 出版年：2011
• 期刊代码：pca254_00257753
• 类别：med
• 出版时间：11 June 2011
• 卷：137
• 期：1
• 页码：14-16
• 文件大小：153 K

Patients and method

We studied the use of anticoagulation following cardioversion due to persistent atrial fibrillation in 422 patients with low or moderate risk of embolism, as well as its benefit during a follow-up of one year.

Results

Oral anticoagulation was maintained after the first month in 80%of patients who showed sinus rhythm and in 43%after 12 months. Its maintenance in patients in sinus rhythm was related to a trend to lower incidence of embolic events (2.8%vs. 0.7%; p = 0.37). The incidence of major bleeding in patients who remained on oral anticoagulation was 4.9%, and age 鈮?5 years (OR 5.3; p = 0.02) was the only independently related factor.

Conclusions

Anticoagulation is frequently maintained to long-term in patients without high risk of embolism but it seems that this treatment doe not have a favorable risk profile with a CHADS₂ = 0 or 1 older than 鈮?5.