Microwave assisted solvent free synthesis of 伪,维-bis (arylidene) cycloalkanones by sulfated zirconia catalyzed cross aldol condensation of aromatic aldehydes and cycloalkanones
- 作者：Kirat Rawal ; Manish Kumar Mishra ; manishorgch@gmail.com ; Manish Dixit ; Meka Srinivasarao
- 关键词：Acid catalysis ; Brø ; nsted acidity ; Cross aldol condensation ; Claisen Schmidt reaction ; Microwave irradiation ; Sulfated zirconia
- 刊名：Journal of Industrial and Engineering Chemistry
- 出版年：2012
- 期刊代码：P29_1226086x
- 类别：ce
- 出版时间：25 July, 2012
- 卷：18
- 期：4
- 页码：1474-1481
- 文件大小：1032 K
摘要
The catalytic application of sulfated zirconia as solid Br酶nsted acid catalyst was explored for cross aldol condensation reactions (Claisen Schmidt reaction). The synthesized catalyst was highly active for solvent free synthesis of 伪,维-bis(arylidene)cycloalkanones by cross aldol condensation of aromatic aldehydes with cycloalkanones. The microwave assisted synthesis resulted increased yields of the products (79-99%) at significantly lower reaction temperature (120-140 掳C) and reaction time (20 min) as compared to the synthesis by thermal heating (63-96%yield at 170 掳C after 4 h). The microwave irradiation afforded selectively cross aldol products. The catalyst could be easily regenerated and reused several times with similar efficiency.