Contactless conductivity detection for microfluidics: Designs and applications
- 作者：Martin Pumera
- 关键词：Contactless conductivity detection ; Microfluidics ; Lab-on-a-chip ; Microchip electrophoresis ; Review
- 刊名：Talanta
- 出版年：2007
- 期刊代码：106_00399140
- 类别：ch
- 出版时间：15 December 2007
- 卷：74
- 期：3
- 页码：358-364
- 文件大小：651 K
摘要
Different methods for construction of contactless conductivity detectors (CCD) for microchip electrophoresis device are described in this review. This includes three main schemes of CCD for microchips, such as (i) the detection electrodes are placed along the microchannel from outside of the microchip and they are insulated from the channel by the cover lid of microchip device; (ii) the electrodes are placed across of the microchannel in the same plane and they are insulated by thin separation channel walls and (iii) electrodes are buried in widened part of microchannel and they are insulated from solution by ultrathin layer of silicon carbide. Specific issues related to the CCD on microfluidics are discussed, such as an influence of shape and magnitude of ac voltage and placement of electrodes and their insulation. Various applications for security, pharmacological, bioassays and food analysis purposes are described.