Does post-mastectomy radiotherapy represent a contraindication to skin-sparing mastectomy and immediate reconstruction: An update

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• 作者：K. Lambert^a ; ^b ; ^{kellylambert@hotmail.com} ; K. Mokbel^b
• 关键词：Breast reconstruction ; Radiotherapy ; Immediate-delayed ; Breast cancer ; Skin-sparing mastectomy
• 刊名：Surgical Oncology
• 出版年：2012
• 期刊代码：245_09607404
• 类别：med
• 出版时间：June, 2012
• 卷：21
• 期：2
• 页码：e67-e74
• 文件大小：482 K

摘要

The use of skin-sparing mastectomy (SSM) to facilitate breast reconstruction is increasing due to a wide acceptance of improved cosmetic outcomes and evidence of equivalence in oncologic outcomes. The rates of patients undergoing mastectomy for whom post-mastectomy radiotherapy (PMRT) will be recommended is increasing as evidence of decreased loco-regional recurrence and increased survival mounts.

PMRT may adversely effect complication rates and cosmetic outcomes for patients undergoing immediate breast reconstruction and PMRT - although the evidence for this is methodologically flawed.

This article summarises the above evidence and highlights a reconstructive algorithm that may be used to mitigate the possible deleterious effects of PMRT on results.