Characterization of thin poly(pyrrole-benzophenone) film morphologies electropolymerized on indium tin oxide coated optic fibers for electrochemical and optical biosensing
- 作者：T. Konry ; Y. Heyman ; S. Cosnier ; K. Gorgy ; R.S. Marks
- 关键词：Immunosensor ; Poly(pyrrole-benzophenone) ; Cholera toxin subunit B ; Scanning electron microscopy
- 刊名：Electrochimica Acta
- 出版年：2008
- 期刊代码：30_00134686
- 类别：ch
- 出版时间：30 June 2008
- 卷：53
- 期：16
- 页码：5128-5135
- 文件大小：877 K
摘要
We report that electropolymerization parameters (duration and voltage) modulate the properties and morphological structures of photoactive polymers which influence both the efficiency of bioreceptor attachment to the polymer surface, and the resulting biosensor assay performance. We have compared two biosensor technologies, optical and electrochemical, for the detection of anti-cholera toxin antibodies using our singular conductive optic fibers, albeit at this stage in separate experiments. Both biosensor systems were more sensitive than conventional detection and pave the way for the possibility to one day make simultaneous optical and electrochemical sensing using the same biosensor.