• 作者：Aldina Couso Gonzá ; lez ; ^{aldinacouso@hotmail.com} ; Juan Antonio Solano Calvo ; Elena Martí ; nez Gó ; mez ; Pedro Fuentes Castro ; Á ; lvaro Zapico Goñ ; i
• 关键词：Pó ; lipo endometrial ; Potencial maligno ; Histeroscopia
• 刊名：Progresos de Obstetricia y Ginecolog铆a
• 出版年：2010
• 期刊代码：pca294_03045013
• 类别：med
• 出版时间：February 2010
• 卷：53
• 期：2
• 页码：46-50
• 文件大小：119 K

Objectives

To determine the pre-malignant and malignant potential of endometrial polyps, and to asses whether different clinical parameters are associated with malignancy in the polyps.

Material and methods

452 hysteroscopic resections of endometrial polyps were reviewed. Histological diagnosis and clinical characteristics (presence of abnormal uterine bleeding and polyp size) were analyzed. Statistical analysis was performed.

Results

The study included 203 pre-menopausal and 249 post-menopausal women. The mean age of pre-menopausal women was 44.3 卤 0,4 years, and 59.1 卤 0.5 years for postmenopausal women. The diagnosis of polyps was by ultrasound with or without hysterosonography, or by hysteroscopy. The main indication of hysteroscopy was abnormal uterine bleeding, which was 65.1%in the pre-menopausal group and 74.7%in the post-menopausal group. There were 23 cases (11.3%) of hyperplasia without atypia in the pre-menopausal group, and 8 cases (3.2%) in the post-menopausal group. Hyperplasia with atypia was found in 2 cases (0.9%) in the pre-menopausal group, and in 9 cases (3.6%) in the post-menopausal group. There were 16 cases of endometrial carcinoma (6.4%), all of them in post-menopausal women. In 1 of these 16 patients there was no abnormal bleeding, but an endometrial polyp was suspected in the ultrasound. Menopause status was significantly associated with pre-malignant or malignant changes. No significant association was found between the presence of abnormal uterine bleeding and polyp size with pre-malignancy or malignancy in the polyp.

Conclusions

Post-menopausal women with endometrial polyp, whether symptomatic or not, should be evaluated by hysteroscopic resection. Asymptomatic pre-menopausal patients, without any risk factor, should be followed up.