Effects of phenol in antioxidant metabolism in matrinxã, Brycon amazonicus (Teleostei; Characidae)
- 作者：Ive Marchioni Avilez ; Tiago Silvestre Fern ; es Hori ; Luciana Cristina de Almeida ; Araceli Hackbarth ; Jayme da Cunha Bastos Neto ; Vera Lucia Freire da Cunha Bastos ; Gilberto Moraes
- 关键词：Antioxidant embolism ; Fish ; Oxidative stress ; Phenol
- 刊名：Comparative Biochemistry and Physiology ; Part C
- 出版年：2008
- 期刊代码：8_15320456
- 类别：pha
- 出版时间：August 2008
- 卷：148
- 期：2
- 页码：136-142
- 文件大小：205 K
摘要
Parameters of the antioxidant defense systems of Brycon amazonicus (matrinxã — a neotropical fish) exposed to phenol for 96h plus the recovery over 1 and 2weeks were studied in erythrocytes and liver. Hematocrit increase was observed during phenol exposure and recovery for 1week. Total superoxide dismutases (SOD), glutathione peroxidase (GPx) and reduced glutathione (GSH) did not change during phenol exposure. Erythrocyte glucose-6-phosphate dehydrogenase (G6PDH) increased during that period while catalase (CAT) activity decreased during phenol exposure and recovery for 2weeks. In the liver, SOD and CAT did not change, whereas GPx increased in the first week of recovery and decreased after 2weeks. A late response was observed for G6PDH activity which increased only at the second week. Ascorbate concentration in the brain decreased during phenol exposure and increased over recovery. From our results it appears that the oxidative stress was limited in matrinxã exposed to phenol, but seemed to occur during the recovery period.