Ex聽Vivo Lung Sonography: Morphologic-Ultrasound Relationship
- 作者：Gino Soldati&lowast ; ; Riccardo Inchingolo&dagger ; ; r_inchingolo@virgilio.it ; Andrea Smargiassi&dagger ; ; Sara Sher&Dagger ; ; Rosanna Nenna§ ; ; Cosimo Damiano Inchingolo§ ; ; Salvatore Valente&dagger ;
- 关键词：Chest sonography ; Ultrasound lung artifacts ; Lung US/histologic relationship ; Lung density ; Porosity ; Alveolar-interstitial syndrome
- 刊名：Ultrasound in Medicine and Biology
- 出版年：2012
- 期刊代码：82_03015629
- 类别：ph
- 出版时间：July, 2012
- 卷：38
- 期：7
- 页码：1169-1179
- 文件大小：1424 K
摘要
Ultrasound (US) interstitial syndrome is a sonographic lung pattern characterized by the presence of acoustic artifacts (B-lines and white lung). The purpose of this study was to demonstrate how interstitial syndrome is determined by acoustic interactions in lungs of variable density and in healthy organs deflated to a nonphysiologic level of density. Normal rabbit lungs were studied ex聽vivo by US at varying known degrees of inflation, and their histologic appearances were described. In this experimental setting, US interstitial syndrome recognizes a mechanism related to tissue density or porosity. Artifacts (B-lines and white lung) appear in the normal rabbit lung through air-dependent increases in density. As in pathologic conditions, US interstitial syndrome can be reproduced in histologically normal lungs that are deflated to a critical level (>0.45 g/mL) of density, which is not achievable under physiologic conditions.