• 作者：H. Portilla-Quattrociocchi ; ^{hportilla@gmail.com} ; I. Banzo ; I. Mart&#237 ; nez-Rodr&#237 ; guez ; R. Quirce ; J. Jimé ; nez-Bonilla ; M. de Arcocha Torres ; P. Medina-Quiroz ; R. del Castillo ; A. Rubio-Vassallo ; J.M. Carril
• 关键词：Cá ; ncer de pulmó ; n ; Gammagrafí ; a ó ; sea ; FDG PET/TAC ; Metá ; stasis ó ; seas
• 刊名：Revista Espa帽ola de Medicina Nuclear
• 出版年：2011
• 期刊代码：pca315_02126982
• 类别：med
• 出版时间：January-February 2011
• 卷：30
• 期：1
• 页码：2-7
• 文件大小：297 K

Objective

To compare the bone scintigraphy (BS) findings and PET/CT scintigraphy with FDG (FDG PET/CT) in the detection of bone metastases in lung cancer.

Material and methods

We studied 32聽patients with lung cancer who underwent FDG PET/CT and BS in a period of 15.9 卤 18.6聽days. The results of both techniques were compared with the histology, where available, radiological structural techniques and the clinical follow-up. In 30聽patients, a definitive diagnosis was reached with the scintigraphic findings. No final diagnosis was obtained in 2聽patients.

Results

BS was positive in 25/30聽patients (83.3%) and negative in 5聽patients. FDG PET/CT was positive in 21/30聽patients (70%) and negative in 9. The BS and the FDG PET/CT were positive in 19/30聽patients (63.3%) for the detection of bone metastases. In 6/19, both techniques showed the same number of bone lesions. In 10/19, FDG PET/CT showed a greater number of bone metastases than BS. In 3/19聽patients, BS showed more lesions than FDG PET/CT and in 2/30聽patients (6.6%), the BS was normal and the FDG PET/CT showed bone lesions which were confirmed as metastasis. In 6/30聽patients (20%), the FDG PET/CT was negative and the BS was positive. BS and FDG PET/CT scan were normal in 3/30聽patients (10%).

Conclusions

In patients with lung cancer, FDG PET/CT scan detected more metastatic bone lesions than BS. It also identified bone metastasis in negative BS. In our experience, when the BS was positive and the FDG PET/CT scan was negative, the lesions observed were mostly related with degenerative bone conditions and bone fractures. In the clinical practice, the FDG PET/CT and BS have a complementary role for the assessment of bone status in lung cancer patients.