Interaction between PAMAM鈥怤H₂ G0 dendrimer and dissociated sodium chloride in aqueous solution

详细信息	查看全文 | 推荐本文 |

• 作者：Adam Buczkowski^a ; Pawel Urbaniak^b ; Joanna Stawowska^c ; Stanislaw Romanowski^d ; Bartlomiej Palecz^a ; ^{paleczb@uni.lodz.pl}
• 关键词：Isothermal titration calorimetry (ITC) ; Conductometry ; Density functional calculations (DFT) ; PAMAM G0 dendrimer ; Sodium chloride
• 刊名：Journal of Molecular Liquids
• 出版年：2012
• 期刊代码：61_01677322
• 类别：ch
• 出版时间：July, 2012
• 卷：171
• 期：Complete
• 页码：54-59
• 文件大小：636 K

摘要

The protonation constants of poly(amidoamine) dendrimer (PAMAM-NH₂ G0) in an aqueous solution of sodium chloride with an ionic strength of 0.05 M were determined by the potentiometric method. The interaction between PAMAM-NH₂ and sodium chloride dissociated in water at room temperature was assessed by means of calorimetric and conductometric measurements. Using isothermal calorimetric titration, the number of the moles of dissociated electrolyte combined by a dendrimer mole was estimated. The conductometric measurements indicate a decrease in electrolyte conductivity in the dendrimer solution in relation to the electrolyte solution and confirm that the dendrimer investigated combines electrolyte ions. The results of DFT calculations performed for the protonated structure of PAMAM-NH₃⁺ suggest that the chlorine atom considered is combined with terminal amino groups, which confirms the results of calorimetric and conductometric measurements.