Synthetic, spectral, thermal and antimicrobial studies on some mixed 1,3-dithia-2-stannacyclopentane derivatives with dialkyldithiocarbamates

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• 作者：Chauhan ; H.P.S. ; Shaik ; Nagulu Meera
• 关键词：Tin(IV) ; 1 ; 2-Dithiolates ; Dialkyldithiocarbamates ; Thermal studies ; NMR ; Antimicrobial activity
• 刊名：Journal of Inorganic Biochemistry
• 出版年：2005
• 期刊代码：53_01620134
• 类别：ch
• 出版时间：February, 2005
• 卷：99
• 期：2
• 页码：538-545
• 文件大小：402 K

摘要

1,3-Dithia-2-stannacyclopentane derivatives with dialkyldithiocarbamates of the types (I) and (II) (where R=CH₃, C₂H₅ and 芒芒芒CH₂芒芒芒CH₂芒芒芒) have been synthesized by the reaction of 2,2-dichloro-1,3-dithia-2-stannacyclopentane and sodium/ammonium salts of dialkyldithiocarbamates in 1:1 and 1:2 molar ratios, respectively, in anhydrous benzene. These newly synthesized derivatives have been characterized by elemental analyses (C, H, N, S and Sn), thermal [thermogravimetry (TG) and differential thermal analyses (DTA)] as well as spectral [UV, IR and multinuclear NMR (¹H, ¹³C and ¹¹⁹Sn)] studies. The monodentate behaviour of the dialkyldithiocarbamate ligands was confirmed by IR and ¹¹⁹Sn NMR spectral data and distorted tetrahedral structures have been suggested for both type (I) and (II) compounds. The free ligands and their tin complexes have also been screened for their antibacterial and antifungal activities. These results made it desirable to delineate a comparison between free ligands and their tin complexes. These exhibit higher antibacterial effect than some of the previously investigated antibiotics.