Density spectral array analysis of SREDA during EEG-video monitoring

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• 作者：Robert P. Carson ; Bassel W. Abou-Khalil ; ^{bassel.abou-khalil@vanderbilt.edu}
• 关键词：SREDA ; Quantitative EEG ; DSA ; Density spectral array ; Benign variants ; Lorazepam
• 刊名：Clinical Neurophysiology
• 出版年：2012
• 期刊代码：61_13882457
• 类别：med
• 出版时间：June, 2012
• 卷：123
• 期：6
• 页码：1096-1099
• 文件大小：2150 K

摘要

Objective

To report the temporal pattern of subclinical rhythmic electrographic discharge of adults (SREDA) and its response to lorazepam during EEG-video monitoring.

Methods

We recorded EEG-video for 3 days in a patient with SREDA, who was previously misdiagnosed with generalized epilepsy. Because SREDA had a very prominent signature on density spectral array (DSA), we used DSA to study the pattern of SREDA over the diurnal cycle, and the response to intravenous lorazepam.

Results

SREDA occurred in both waking and sleep, but tended to occur in single bursts in waking and in longer clusters during sleep. Lorazepam suppressed SREDA.

Conclusions

The temporal pattern of SREDA varies during the sleep-wake cycle. Lorazepam appears to suppress SREDA.

Significance

Response to lorazepam cannot distinguish SREDA from electrographic seizure activity.