Mise au point d鈥檜ne technique multiplex de d茅pistage g茅nomique HEV-HAV
- 作者：C. Merviel ; cmerviel@gmail.com ; J.-M. Mansuy ; M. Dubois ; J. Izopet
- 关键词：Hé ; patite E ; Zoonose ; Infection ; Ictè ; re ; Virus ; Biologie molé ; culaire ; RT-PCR ; Multiplex
- 刊名：Pathologie Biologie
- 出版年：2012
- 期刊代码：216_03698114
- 类别：med
- 出版时间：April, 2012
- 卷：60
- 期：2
- 页码：95-105
- 文件大小：329 K
摘要
The hepatitis E virus (HEV) is more and more frequently incriminated in hepatitis episodes. In non-endemic regions, it is clear now that this infection is autochthonous, and certainly a zoonosis and thus, that this virus must not only be assessed in hepatitis cases among travellers in endemic regions. In parallel, in endemic region, where HEV, like HAV, is mainly water-transmitted, important outbreaks still occur. This article describes the development and validation of a new molecular technique for detecting simultaneously HAV RNA and HEV RNA and its evaluation on clinical specimen.