Inequality in sentinel lymph node dissection for elderly women with early stage breast cancer: Results from a French prospective cohort study

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• 作者：Camille Cluze^a ; ^b ; ^c ; ^{camille.cluze@inserm.fr}  ; [Author Vitae] ; Fré ; dé ; rique Retornaz^d ; ^e ; Dominique Rey^a ; ^b ; ^c ; Mé ; gane Meresse^a ; ^b ; ^c ; Fré ; dé ; rique Rousseau^f ; Anne-Dé ; borah Bouhnik^a ; ^b ; ^g ; Roch Giorgi^h ; ⁱ
• 关键词：Breast neoplasm ; Sentinel lymph node dissection ; Axillary lymph node dissection ; Elderly
• 刊名：Journal of Geriatric Oncology
• 出版年：2012
• 期刊代码：pca13_18794068
• 类别：bio
• 出版时间：July, 2012
• 卷：3
• 期：3
• 页码：212-219
• 文件大小：276 K

摘要

Objective

To identify factors associated with under-use of sentinel lymph node dissection (SLND).

Materials and Methods

This study was performed in ELIPPSE 65, a representative cohort of women aged 鈮?#xA0;65 with breast cancer. We included all women eligible for SLND. Characteristics of those who had received SLND - whether or not axillary lymph node dissection (ALND) was subsequently carried out - were compared with those having received immediate ALND without prior SLND.

Results

A total of 349 women were eligible for SLND. After excluding those without surgery or with unknown axillary surgery type, 337 women were analyzed. Immediate ALND was performed in 20%of cases. Immediate ALND had been performed more frequently in women aged 鈮?#xA0;75 and in those who had poor family support.

Conclusion

Although SLND is a widespread surgical practice, many women still have unnecessary ALND. This is particularly detrimental for elderly women as their life may be strongly impaired by lymphedema.