- 作者：Mario H. Vargas<sup>asup><sup> ; sup><sup>mhvargasb@yahoo.com.mxsup> ; Irasema Rodrí ; guez-Godí ; nez<sup>bsup> ; Jesú ; s Arias-Gó ; mez<sup>csup><sup> ; sup><sup>dsup> ; M. Elena Y. Furuya<sup>asup>
- 关键词：Ritmo circadiano ; Saturació ; n de hemoglobina ; Funció ; n pulmonar
- 刊名：Archivos de Bronconeumolog铆a
- 出版年：2012
- 期刊代码：pca65_03002896
- 类别：med
- 出版时间：June, 2012
- 卷：48
- 期：6
- 页码：202-206
- 文件大小：658 K
ss="h4">Background
Peripheral oxygen saturation (SpO<sub>2sub>) measured by pulse oximetry is widely used in clinical practice, but its fluctuations over the course of the 24 h of a day have not been explored at length. Recently, we reported that children hospitalized due to non-cardiopulmonary causes had a circadian variation in SpO<sub>2sub>. This finding needed to be corroborated in healthy children, which is the objective of the present study.
ss="h4">Patients and methods
Healthy children residing in a state foster home were studied with pulse oximetry every 2 h for 24 h.
ss="h4">Results
Eighty two children were included in the study, ranging in age from one month to 6.5 years (average 卤 standard error of 3.06 卤 0.16 years), with a weight-for-length/height percentile of 65.5 卤 2.9. In 65 (79.3%) children, the SpO<sub>2sub> levels followed a sinusoidal curve suggesting circadian rhythm. The total group of sinusoidal curves in this population had a mesor of 95.10 卤 0.08% SpO<sub>2sub>, period of 21.05 卤 0.54 h (in 53.8%of these children, the period was between 20 and 28 h). The maximum SpO<sub>2sub> was reached at 3:14 PM 卤 16 min, and the minimum at 5:16 AM 卤 48 min. When the 24 h were divided into four periods, it was demonstrated that the highest SpO<sub>2sub> levels were reached between 2 PM and 8 PM.
ss="h4">Conclusions
In this population of clinically healthy children, there was a circadian variation in pulse oximetry, with maximum values in the late afternoon and minimal values in the early morning.