Cytochromes P460 and c′-beta; A new family of high-spin cytochromes c

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• 作者：Bradley O. Elmore ; David J. Bergmann ; Martin G. Klotz ; Alan B. Hooper
• 关键词：Cytochrome c′ ; Cytochrome P460 ; Denitrification ; N-oxide detoxification ; Bacterial enzyme evolution
• 刊名：FEBS Letters
• 出版年：2007
• 期刊代码：70_00145793
• 类别：bio
• 出版时间：6 March 2007
• 卷：581
• 期：5
• 页码：911-916
• 文件大小：360 K

摘要

Cytochromes-P460 of Nitrosomonas europaea and Methylococcus capsulatus (Bath), and the cytochrome c′ of M. capsulatus, believed to be involved in binding or transformation of N-oxides, are shown to represent an evolutionarily related new family of monoheme, 17 kDa, cytochromes c found in the genomes of diverse Proteobacteria. All members of this family have a predicted secondary structure predominantly of beta-sheets in contrast to the predominantly alpha-helical cytochromes c′ found in photoheterotrophic and denitrifying Proteobacteria.