• 作者：Á ; ngel Celada Rodrí ; guez^a ; Pedro Juan Tá ; rraga L&#243 ; pez^b ; ^{pedrojuan.tarraga@uclm.es} ; José ; Antonio Rodrí ; guez Montes^c ; Juan Solera Albero^b ; Mateo A. L&#243 ; pez Cara^a ; Enrique Arjona Laborda^a
• 关键词：Disfunció ; n eré ; ctil ; Riesgo cardiovascular ; Í ; ndice aterogé ; nico
• 刊名：Cl铆nica e Investigaci贸n en Arteriosclerosis
• 出版年：2011
• 期刊代码：pca88_02149168
• 类别：med
• 出版时间：November-December 2011
• 卷：23
• 期：6
• 页码：253-261
• 文件大小：378 K

lass="h4">Objectives

To determine the prevalence of erectile dysfunction (ED) in patients with cardiovascular risk factors (CVRF) and to evaluate the incidence of this disorder according to the degree of control of CVRF.

lass="h4">Methodology

Participants were recruited in the health centers included in this study. A sample size with 95%confidence level and an alpha error of 0.005 was calculated and 210 persons were selected, of which 30 could not complete the study for various reasons (change of address, death, refusal to complete the questionnaire, etc.).

A previously designed data collection sheet and the SHIM and LISAT-8 questionnaires were completed at interview.

The study design was observational, descriptive, analytical cross-sectional. Qualitative variables are shown as exact values and as percentages and qualitative variables as means and standard deviation (SD).

Comparison among means was performed using Student's t-test for independent samples or the Mann-Whitney U-test if the conditions of normality (application of the Kolmogorov-Smirnoff or Shapiro-Wilks鈥?test) were not met. For qualitative variables, the chi-square test was used.

lass="h4">Results

Of the 210 persons selected, 179 (85.2%) completed the survey correctly. The mean age was 64.5 卤 11.6 years. Analysis of all the study variables in relation to the main variable of the presence or absence of ED revealed that age played a major role, with the incidence of ED increasing with greater age.

ED was significantly associated with the atherogenic index and with this variable recodified in high or low atherogenic risk (P < .04). Diabetic diseases, hypertension and dyslipidemia were not significantly associated with the presence of ED separately but a significant association was found when these diseases were associated, due to the increase in cardiovascular risk, according to the Framingham tables. The duration of each disease was not significantly associated with the presence of ED. No significant differences were found in the presence of ED according to the drugs used for the treatment of these three diseases.

Coronary risk calculated according to Framingham tables, as well as excess risk (the difference between coronary risk and mean risk assigned to each age group), showed a statistically significant association with the presence of ED.

The drugs used to treat cardiovascular risk factors showed a nearly statistically significant association with the presence of ED (P < .07).

In this study, the LISAT-8 questionnaire demonstrated that ED affected health-related quality of life, showing a significant association with the items of sexual life and economic position, and was nearly significantly associated with the items of life in general and occupational life.

lass="h4">Conclusions

The prevalence of ED is high in patients with high cardiovascular risk, indicating the need for better control of CVRF, which would undoubtedly improve this disorder. The presence of multiple diseases in these patients requires careful evaluation of the need for intensive polymedication, which undoubtedly increases the risk of ED.