An epidemiological survey of hymenoptera venom allergy in the Spanish paediatric population

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• 作者：A. Martí ; nez-Cañ ; avate^a ; ^{anamartinezcanavate@gmail.com} ; A.I. Tabar^b ; J.L. Eseverri^c ; F. Martí ; n^d ; C. Pedemonte-Marco^e ; ^f
• 关键词：Anaphylaxis ; Hymenoptera ; Immunotherapy ; Children
• 刊名：Allergologia et Immunopathologia
• 出版年：2010
• 期刊代码：pca44_03010546
• 类别：med
• 出版时间：September-October 2010
• 卷：38
• 期：5
• 页码：259-262
• 文件大小：211 K

摘要

Hypersensitivity reactions to hymenoptera venom are infrequent in paediatric patients. A study was made to determine the incidence of this pathology in children, based on an epidemiological survey targeted to all members of the SEICAP (Sociedad Espa帽ola de Inmunolog铆a Cl铆nica y Alergia Pedi谩trica/Spanish Society of Paediatric Clinical Immunology and Allergy), and designed to collect the data on patients under 17 years of age diagnosed with hymenoptera venom allergy. Results: The data corresponding to 175 patients (135 males) were collected. The mean age was 9.9卤3.6 years. Seventeen percent (32 patients) were the offspring of beekeepers, and 68.9%had experienced previous stings. The causal insect was Apis melifera, implicated in 55 cases, followed by Polistes dominulus (33 cases). In 151 patients (83.9%) the condition consisted of a local reaction. The most frequent systemic response was urticaria and angio-oedema. Fourteen patients suffered anaphylactic shock. The diagnosis was based on skin test (intradermal and prick) and/or specific IgE testing. Three treatment categories were established: (a) prevention and educational measures; (b) symptomatic treatment with oral antihistamines as well as self-injectable adrenalin; and (c) immunotherapy. In this context, 135 patients underwent immunotherapy with a mean duration of 3.5卤1.7 years (range 2鈥? years) 鈥?with excellent tolerance. The starting regimen was predominantly conventional (92 patients). Conclusions: The results of this survey show hypersensitivity reactions to hymenoptera venom to be infrequent in paediatrics, though with a strong impact upon patient quality of life.