摘要
The gradient pulses of double-GBIRD can be replaced with high-power spin-lock pulses (RF gradients) inz-rotation composite sandwiches. Implementation of this double-spin-locked BIRD (double-SLBIRD) in 2D HSQC results in drastic suppression oft1noise, nice baseline characteristics, and good dynamic range. The superior properties of double-SLBIRD-HSQC over conventional HSQC and even over double-spin-locked HSQC for small to medium-sized molecules makes this excitation-sculpting approach preferable. However, double-SLBIRD should not be considered as an alternative for double-GBIRD, but rather as a substitute for those spectrometers lacking field gradients.