- 作者：Mauricio Sarmiento-Chavero ; Nayeli Belem Gabiñ ; o-Ló ; pez ; benith11@hotmail.com ; Ana De Cosio-Farias ; Mariam Smith-Pliego ; Marco Antonio Durá ; n-Padilla
- 关键词：Linfoma ; MALT ; Conjuntiva
- 刊名：Revista Espa帽ola de Patolog铆a
- 出版年：2011
- 期刊代码：pca318_16998855
- 类别：med
- 出版时间：July-September 2011
- 卷：44
- 期：3
- 页码：173-178
- 文件大小：299 K
Introduction
Lymphoid ocular adnexa neoplasms comprise 7-8%of all extranodal lymphomas, the most common being the extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma), followed by diffuse large B-cell lymphoma. Some infectious organisms may play an aetiological role in the development of MALT lymphomas, although this is not a consistent finding. Specific translocations have also been identified which cause activation of nuclear factor bound to the promoter kappa light chains of activated B-lymphocites (NF-kB). MALT lymphomas are the predominant type of lymphoma in the conjunctiva and other occular adnexa. They occur more frequently in females and the average age of patients is 61; they are extremely rare before the age of 25.
Material and methods
Clinical and morphological data from biopsies diagnosed as MALT lymphoma, from the General Hospital of Mexico during the years 2003 to 2010, were reviewed.
Results
Of the 12 cases found, the age range was 23 to 74, with an average age of 50.7; 7 (58.3%) were female and 5 (41.6%) were male. The morphology of the present cases was that of small lymphocytic lymphoma (MALT lymphoma) and the diagnosis was confirmed by immunohistochemistry.