Incidence of lower limb amputations in individuals with and without diabetes mellitus in Andalusia (Spain) from 1998 to 2006

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• 作者：Maria Cruz Almaraz^a ; ^b ; ^e ; ^{malmaraza@hotmail.com} ; Stella Gonzá ; lez-Romero^a ; ^b ; ^e ; ^{stellagr@telefonica.net} ; Manuel Bravo^a ; ^c ; ^{mbravob2001@yahoo.es} ; Fé ; lix Francisco Caballero^d ; ^{ffcaballero23@hotmail.com} ; Maria José ; Palomo^a ; ^b ; ^{mariajosepalomofdez@hotmail.com} ; Rosario Vallejo^a ; ^b ; ^{rosariovallejomora@hotmail.com} ; Isabel Esteva^b ; ^e ; ^{miesteva@wanadoo.es} ; Fernando Calleja^a ; ^f ; ^{fkyeja@terra.es} ; Federico Soriguer^a ; ^b ; ^e ; ^{federico.soriguer.sspa@juntadeandalucia.es}
• 关键词：Amputations ; Diabetic foot ; Diabetes ; Epidemiology
• 刊名：Diabetes Research and Clinical Practice
• 出版年：2012
• 期刊代码：78_01688227
• 类别：med
• 出版时间：March, 2012
• 卷：95
• 期：3
• 页码：399-405
• 文件大小：302 K

摘要

Aims

We studied the changes in the incidence of lower limb amputation (LLA) in Andalusia from 1998 to 2006 in the population with and without diabetes.

Methods

We undertook a retrospective study of all LLA performed in Andalusia in people aged 30 years old, with or without diabetes, between 1 January 1998 and 31 December 2006. We obtained the crude and standardized incidence rates by year, and sex for three periods: 1998-2000, 2001-2003 and 2004-2006 and calculated the RR of requiring LLA in patients with diabetes. To test for time trend, Poisson regression models were fitted.

Results

A total of 16,210 LLA were carried out in Andalusia, 72.6%in patients with diabetes mellitus and 66.4%in men. In the population with diabetes the standardized incidence of all LLA was found to be 344.0 per 100,000 (95%CI, 315.4-372.4) in 2004-2006. There was an estimated incidence increase for all LLA by 14%and for minor LLA by 13.6%in 2004-2006. In people with diabetes the RR increased by 31.6%as compared to the first period.

Conclusions

Despite the implementation of a care plan for patients with diabetes, the incidence of LLA has not fallen in Andalusia in recent years.