Early-onset obsessive–compulsive disorder and personality disorders in adulthood
- 作者：Giuseppe Maina ; Umberto Albert ; Virginio Salvi ; Enrico Pessina ; Filippo Bogetto
- 关键词：OCD ; Early-onset ; Personality disorders ; OCPD
- 刊名：Psychiatry Research
- 出版年：2008
- 期刊代码：225_01651781
- 类别：med
- 出版时间：15 March 2008
- 卷：158
- 期：2
- 页码：217-225
- 文件大小：166 K
摘要
Obsessive–compulsive disorder (OCD) often emerges in childhood or adolescence. The aim of the present study was to evaluate whether adult patients with prepuberal onset differ from subjects with later onset in terms of personality disorder comorbidity. The Structured Clinical Interview for DSM-IV Axis II Disorders was used to assess 148 patients with a principal diagnosis of OCD according to the Structured Clinical Interview for DSM-IV Axis I Disorders. The following two subgroups of subjects were selected according to the age at onset of symptomatology: patients with an early-onset (≤ 10 years), and patients with a later onset (≥ 17 years). Of the 148 patients screened for the present study, 33 (22.3%) had an early onset and 13 69 (46.6%) had a later onset. With regard to personality disorders, early-onset patients showed more OC personality disorders (OCPD) than later onset patients. Our finding suggests that OCD in childhood increases the risk for developing OCPD in adulthood, or that early-onset OCD and OCPD share a common pathogenesis.