• 作者：José ; Mancera Romero^a ; ^{jmancerar@papps.org} ; Francisca Paniagua Gó ; mez^a ; Ildefonso Martos Cerezuela^b ; Antonio Baca Osorio^a ; Salvador Ruiz Vera^b ; Pedro Gonzá ; lez Santos^c ; Pedro Valdivielso Felices^c
• 关键词：Diabetes ; Enfermedad arterial perif&eacute ; rica ; Í ; ndice tobillo-brazo
• 刊名：Cl铆nica e Investigaci贸n en Arteriosclerosis
• 出版年：2010
• 期刊代码：pca88_02149168
• 类别：med
• 出版时间：July-August 2010
• 卷：22
• 期：4
• 页码：154-161
• 文件大小：189 K

class="h4">Introduction

The aim of our study was to estimate the prevalence and associated factors of occult peripheral arterial disease (PAD) assessed by the ankle-brachial index (ABI) in subjects with type 2 diabetes mellitus followed up in a single urban Primary Care Center.

class="h4">Methods

This is a cross-sectional study involving subjects who were sampled randomly from patients with type 2 diabetes and aged 50 to 80 years-old. The dependent variable was the presence of PAD, assessed by an ABI below 0.9. Demographic, clinical and laboratory parameters were also recorded. A forward, stepwise, logistic binary regression was built in order to examine variables associated with abnormal ABI.

class="h4">Results

Four-hundred and fifty-six patients were included; they were 61卤6 years-old, of which 243 (53%) were men. An ABI<0.9 was found in 126 patients (27.6%), 310 (68%) patients had an ABI 0.9鈥?.3 and only 20 patients (4.4%) had and ABI higher than 1.3. Using multivariate analyses, past or present smoking, duration of diabetes, platelet count and hypertriglyceridemia, were independently associated to PAD; on the contrary, only waist cincumference and the presence of microvascular disease were associated to an ABI higher than 1.3.

class="h4">Conclusion

The prevalence of PAD was high and consistent with the literature, thus reinforcing the measurement of ABI for all patients with type 2 diabetes followed up in primary care. Smoking, duration of diabetes, platelet count and hypertriglyceridemia were independently associated to a low ABI.