• 作者：A. Barba ; ^{angel.barbavelez@osakidetza.net} ; M. Vega de Cé ; niga ; L. Estallo ; N. de la Fuente ; B. Viviens ; R. Gó ; mez ; R. Sarobe ; M.C. Alvarez-Elizegui
• 关键词：Aneurisma de aorta abdominal ; Cribado poblacional ; Prevalencia ; Varones de 65 a&ntilde ; os
• 刊名：Angiolog铆a
• 出版年：2011
• 期刊代码：pca50_00033170
• 类别：med
• 出版时间：January-February 2011
• 卷：63
• 期：1
• 页码：18-24
• 文件大小：146 K

lass="h4">Objective

To analyse the prevalence of abdominal aortic aneurysms (AAA), risk factors and possible changes in serological parameters in 65-year-old men, born in 1943, registered in the Inner Region of Bizkaia, and to compare this prevalence with that obtained in other previous epidemiological studies performed in 65 to 74-year-old men.

lass="h4">Design

Cross-sectional epidemiological study.

lass="h4">Material and methods

In October-December 2007 the 1,413 men born in 1943 were invited to participate in this study. A physical examination, body mass index (BMI), abdominal ultrasound and general and specific blood tests were performed.

lass="h4">Results

Nineteen (1.3%) of the 1,413 registered men were deceased, 41 openly refused to participate in the study and we could not find the current address of 250 men (17.7%), so the final number of available candidates was 1,103, of whom 781 (70.8%) finally attended their appointments. We diagnosed 37 AAA (4.7%). Men with brothers diagnosed with an AAA, smokers, hypertensive and/or suffering from peripheral arterial disease had a greater probability of developing an AAA, in contrast with diabetic patients, who showed lower risk. The AAA patients had higher levels of metalloproteinase-9 (MMP-9) and C-reactive protein (CRP) than the controls (mean 卤 standard deviation): 5.9 卤 3.9 ng/dl and 4.1 卤 3.4 mg/l versus 4.2 卤 3.4 ng/dl and 2.6 卤 2.5 mg/l; p = 0.0042 and 0.002, respectively.

lass="h4">Conclusion

The prevalence of AAA in 65-year-old men in our area is similar to that described in 65 to 74-year-old men in other previous international studies. Peripheral MMP-9 and CRP levels are increased in AAA patients compared to controls.