Palladium versus copper-catalyzed N-arylation towards an efficient access to polysubstituted dibenzophenanthrolines and carbazoles
- 作者：Jacquelin ; Cl脙脙mence ; Saettel ; Nicolas ; Hounsou ; Candide ; Teulade-Fichou ; Marie-Paule
- 关键词：N-Arylation ; Palladium and copper-catalysis ; Polysubstituted dibenzo-phenanthrolines ; Selective arylation ; Functional carbazoles
- 刊名：Tetrahedron Letters
- 出版年：2005
- 期刊代码：109_00404039
- 类别：ch
- 出版时间：April 11, 2005
- 卷：46
- 期：1
- 页码：2589-2592
- 文件大小：115 K
摘要
The double amination of meta-diiodo and dibromobenzenes by anthranilic acid derivatives is described using palladium and/or copper catalysis. The resulting symmetrical and unsymmetrical phenylene diamines are key precursors to polyfunctional dibenzophenanthroline carboxaldehydes. In contrast, when ortho-dibromo benzene is used as substrate, the Pd-mediated process affords exclusively the functional carbazole.