New Paracoccidioides brasiliensis isolate reveals unexpected genomic variability in this human pathogen
- 作者：Lilia L. Carrero ; Gustavo Niñ ; o-Vega ; Marcus M. Teixeira ; Maria Jose A. Carvalho ; Cé ; lia M.A. Soares ; Maristela Pereira ; Rosá ; lia S.A. Jesuino ; Juan G. McEwen ; Leonel Mendoza ; John W. Tayl
- 关键词：Paracoccidioides brasiliensis ; Molecular phylogeny ; Molecular variability ; Genealogical concordance
- 刊名：Fungal Genetics and Biology
- 出版年：2008
- 期刊代码：116_10871845
- 类别：abs
- 出版时间：May 2008
- 卷：45
- 期：5
- 页码：605-612
- 文件大小：156 K
摘要
By means of genealogical concordance phylogenetic species recognition (GCPSR), we have investigated coding and non-coding regions from various genes and the ITS sequences of 7 new and 14 known isolates of Paracoccidioides brasiliensis. Such isolates grouped within the three phylogenetic groups recently reported in the genus Paracoccidioides, with one single exception, i.e., Pb01, a strain that has been the subject of intense molecular studies for many years. This isolate clearly separates from all other Paracoccidioides isolates in phylogenetic analyses and greatly increases the genomic variation known in this genus.