Synthesis of soluble multivalent glycoconjugates that target the Hc region of botulinum neurotoxin A
- 作者：Ramesh R. Kale ; Colin M. Clancy ; Rebecca M. Vermillion ; Eric A. Johnson ; Suri S. Iyer
- 关键词：Glycoconjugates ; Multivalent ; Botulinum A
- 刊名：Bioorganic and Medicinal Chemistry Letters
- 出版年：2007
- 期刊代码：10_0960894x
- 类别：ch
- 出版时间：1 May 2007
- 卷：17
- 期：9
- 页码：2459-2464
- 文件大小：399 K
摘要
The design, synthesis, and initial inhibitory studies of di- and tetravalent glycoconjugates that target the heavy chain of botulinum neurotoxin A are reported.