- 作者：M. Pilar Garcí ; a Muret ; mgarciam@santpau.cat ; Alba Català ; Gonzalo
- 关键词：Micosis fungoide ; Foliculotropa ; Linfoma cutá ; neo de cé ; lulas T ; Foliculotropismo
- 刊名：Piel
- 出版年：2011
- 期刊代码：pca282_02139251
- 类别：med
- 出版时间：October 2011
- 卷：26
- 期：8
- 页码：378-390
- 文件大小：2061 K
Folliculotropic mycosis fungoides is a relatively uncommon variant of mycosis fungoides characterized by atypical lymphocytes around and within the epithelium of the hair follicles. This entity can present with a wide variety of clinical pictures including acneiform lesions, comedones, cysts, alopecia with or without scarring, and nodular prurigo-like lesions. The head, neck region and upper trunk, are most commonly involved. Pruritus is especially common. From a biologic point of view, the most relevant feature in cases with and without associated follicular mucinosis is the deep, follicular, and perifollicular localization of the neoplastic infiltrates, which makes them less accessible to skin-targeted therapies. This case-based clinicopathologic review provides clinical-pathological, differential diagnostic, prognosis and therapeutic characteristics of this subtype of micosis fungoides.