Involvement of the medial amygdaloid nucleus in restraint stress-induced pressor responses in rats
- 作者：Kubo ; Takao ; Okatani ; Hideaki ; Nishigori ; Yusuke ; Hagiwara ; Yukihiko ; Fukumori ; Ryuji ; Goshima ; Yoshio
- 关键词：Medial amygdala ; Restraint stress ; Pressor response ; Muscimol ; Fos immunoreactivity ; Rat
- 刊名：Neuroscience Letters
- 出版年：2004
- 期刊代码：52_03043940
- 类别：neu
- 出版时间：January 2, 2004
- 卷：354
- 期：1
- 页码：84-86
- 文件大小：98.5 K
摘要
Restraint stress increased the number of neurons with Fos immunoreactivity in the medial amygdaloid nucleus in rats and caused an increase in blood pressure. The stress-induced pressor response was inhibited by muscimol (80 pmol), a neuroinhibitory compound, injected bilaterally into the medial amygdaloid area, whereas muscimol (8 pmol) similarly injected had only a tendency of inhibition of the pressor response. These data suggest that the medial amygdaloid nucleus is involved in mediation of the restraint stress-induced pressor response.