A New Artificial Urinary Sphincter with Conditional Occlusion for Stress Urinary Incontinence: Preliminary Clinical Results

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• 作者：Sarah L. Knight ; Judith Susser ; Tamsin Greenwell ; Anthony R. Mundy and Michael D. Craggs
• 刊名：European Urology
• 出版年：2006
• 期刊代码：289_03022838
• 类别：med
• 出版时间：September 2006
• 卷：50
• 期：3
• 页码：574-580
• 文件大小：246 K

摘要

Objectives

To perform a preliminary clinical investigation to determine the safety and efficacy of a novel artificial urinary sphincter (AUS) with conditional occlusion for the treatment of stress urinary incontinence.

Methods

Male patients with urodynamically proven stress urinary incontinence after a prostatectomy were implanted with the novel AUS. They were followed up over a period of 12 months and the device tested for efficacy by using objective measurements of urinary leakage and continence. We derived a new measure for continence called the Continence Index.

Results

We have demonstrated that the patients receiving the new AUS showed a reduction of greater than 10-fold in mean daily leakage volume from 770.6 ml to 55.1 ml. There was an overall improvement in the Continence Index from 54%to 97%.

Conclusions

The new AUS with conditional occlusion provides good continence rates and enables adjustment of regulating pressure in situ.