Quantitative Ultrasound Criteria for Risk Stratification in Clinical Practice: A Comparative Assessment
- 作者：Marianna Noale&lowast ; ; marianna.noale@in.cnr.it ; Stefania Maggi&lowast ; ; Stefano Gonnelli&dagger ; ; Federica Limongi&lowast ; ; Silvia Zanoni&lowast ; ; Sabina Zambon&lowast ; ; Renzo Rozzini&Dagger ; ; Gaetano Crepaldi&lowast ; ; ESOPO Study Working Group
- 关键词：Quantitative heel ultrasound ; Osteoporosis risk ; Fracture risk ; Risk factors ; ESOPO study
- 刊名：Ultrasound in Medicine and Biology
- 出版年：2012
- 期刊代码：82_03015629
- 类别：ph
- 出版时间：July, 2012
- 卷：38
- 期：7
- 页码：1138-1144
- 文件大小：146 K
摘要
This study aimed to compare two different classifications of the risk of fracture/osteoporosis (OP) based on quantitative ultrasound (QUS). Analyses were based on data from the Epidemiological Study on the Prevalence of Osteoporosis, a cross-sectional study conducted in 2000 aimed at assessing the risk of OP in a representative sample of the Italian population. Subjects were classified into 5 groups considering the cross-classification found in previous studies; logistic regression models were defined separately for women and men to study the fracture risk attributable to groups defined by the cross-classification, adjusting for traditional risk factors. Eight-thousand six-hundred eighty-one subjects were considered in the analyses. Logistic regression models revealed that the two classifications seem to be able to identify a common core of individuals at low and at high risk of fractures, and the importance of a multidimensional assessment in older patients to evaluate clinical risk factors together with a simple, inexpensive, radiation-free device such as QUS.